Prajnaparadha: The Root Cause of Disease Manifestation
Author : Dr. Amit Kosurkar and Dr. Sanjay Kosankar
Abstract :
Prajnaparadha (intellectual blasphemy or failure of wisdom) is regarded in Ayurveda as one of the three principal causes of disease, alongside Asatmya Indriyartha Saṃyoga (improper utilization of sensory organs) and Pariama (Kala) (effects of time). Among these, Acharya Charaka considers Prajnaparadha to be the most significant etiological factor because it originates from the impairment of Dhi (intellect), Dhṛti (self-control), and Smṛti (memory), leading individuals to knowingly engage in unhealthy physical, verbal, and mental actions. Such repeated behavioural errors disturb the equilibrium of Doshas, impair Agni, promote Ama formation, and ultimately manifest as disease. Contemporary medicine similarly recognizes that poor decision-making, maladaptive behaviours, chronic psychological stress, addictions, unhealthy dietary practices, physical inactivity, and emotional dysregulation contribute substantially to the burden of non-communicable and psychosomatic diseases. Thus, the Ayurvedic concept of Prajnaparadha closely parallels modern behavioural medicine and cognitive science. This review critically examines the classical understanding of Prajnaparadha, its role in disease manifestation, and its contemporary relevance by integrating Ayurvedic principles with current evidence from psychology, behavioural neuroscience, and lifestyle medicine. Such an integrative perspective highlights the importance of behavioural modification and preventive healthcare in achieving holistic well-being.
Keywords :
Prajnaparadha, Ayurveda, Dhi, Dhriti, Smrti, Behavioural Medicine, Lifestyle Disorders.
